ABSTRACT
Al cumplirse este año 50 años de la cirugía de bypass coronario, introducida y desarrollada por René Favaloro en la Cleveland Clinic, es conveniente meditar el camino seguido previamente por la cirugía para tratar la enfermedad coronaria, analizar cómo la cirugía enfrenta en la actualidad esta grave y frecuente enfermedad, y, si es posible, predecir el rol que ésta jugará en el futuro en el tratamiento de la enfermedad coronaria.
This year is the 50th anniversary of Coronary Artery Bypass Graft surgery, introduced and developed by René Favaloro at The Cleveland Clinic. The occasion calls for meditation about the path followed by surgery to treat coronary artery disease in the past, to analyze how surgery currently faces this serious and frequent disease and, if possible, to predict the role that surgery will play in the future in the treatment of coronary artery disease.
Subject(s)
History, 20th Century , Coronary Artery Disease/history , Cardiology/history , Cardiac Surgical Procedures/history , Coronary Artery Bypass/historyABSTRACT
Diabetes insipidus (DI) is characterized by excessive urination and thirst. This disease results from inadequate output of antidiuretic hormone (ADH) from the pituitary gland or the absence of the normal response to ADH in the kidney. We present a case of transient central DI in a patient who underwent a cardiopulmonary bypass (CPB) for coronary artery bypass grafting (CABG). A 44-yr-old male underwent a CABG operation. An hour after the operation, the patient developed polyuria and was diagnosed with central DI. The patient responded to desmopressin and completely recovered five days after surgery. It is probable that transient cerebral ischemia resulted in the dysfunction of osmotic receptors in the hypothalamus or hypothalamus-pituitary axis during CPB. It is also possible that cardiac standstill altered the left atrial non-osmotic receptor function and suppressed ADH release. Therefore, we suggest that central DI is a possible cause of polyuria after CPB.